Nitrazepam continues to be related to serious hepatic Problems, just like other nitrobenzodiazepines. Nitrobenzodiazepines for instance nitrazepam, nimetazepam, flunitrazepam, and clonazepam are more harmful into the liver than other benzodiazepines as They are really metabolically activated by CYP3A4 which can lead to cytotoxicity.In case you have